1. Accueil
  2. EN
  3. Studying at ULB
  4. Find your course
  5. UE
MEDI-G4404

Neurosciences (part II) : maladies nerveuses

academic year
2023-2024

Course teacher(s)

Alban DE KERCHOVE D'EXAERDE (Coordinator) and Jerôme Bonnefont

ECTS credits

5

Language(s) of instruction

french

Course content

Pathogenic mechanims in the nervous system: Programmed cell death and necrosis. Defects of DNA repair. Abnormalities of metabolic pathways. Excitotoxicity. Mitochondrial dysfunction. Disturbances of axoplasmic transport. Ubiquitin-proteasome system. Autophagy and intra- and extracellular accumulations of proteins.

Neurodegenerative diseases: Alzheimer's disease. Parkinson's disease. Huntigton's disease. Prions diseases. Amyotrophic lateral sclerosis. Neurogenetic diseases: Metabolic encephalopathies.

Hereditary Neurogenetic diseases: Hereditary diseases of the peripheral nervous system. Genetic epilepsies.

Normal and Pathological Mnesic Processes: Molecular and cellular mecanisms, types of memory, their neural supports and their alterations.

Neuropsychiatric Diseases: Drug addiction, Schizophrenia, Mood Disorders, Anxiety Disorders.

Objectives (and/or specific learning outcomes)

Acquisition of of basic knowledge related to pathologiocal cellular mechanisms of nervous diseases.

Prerequisites and Corequisites

Required and corequired courses

Teaching methods and learning activities

Theoretical courses: lectures.

Contribution to the teaching profile

Acquisition of scientific knowledges.

References, bibliography, and recommended reading

Reviews in scientific articles.

Other information

Contacts

Jean-Pierre Brion (coordonnateur): jpbrion@ulb.ac.be

Massimo Pandolfo:massimo.pandolfo@ulb.ac.be

Alban de Kerchove: Alban.de.Kerchove@ulb.ac.be

Evaluation

Method(s) of evaluation

  • Other

Other

Written examination on the course content.

Mark calculation method (including weighting of intermediary marks)

If the three partial examination marks are equal or above 08/20: Pathogenic mechanisms and neurodegenerative diseases (J.P. Brion): 33 %; Pathogenic mechanisms and Neurogenetic diseases (M. Pandolfo): 33%. Mnesic Processes and Neuropsychaitric diseases (A. de Kerchove): 33%. If a a partai mark is inferior to 08/20, the maximal global examination mark is 07/20.

The examination marks inferior to 10/20 will not benefit from a partial report (J.P.Brion, M. Pandolfo, A. de Kerchove) to the next academic year.

Language(s) of evaluation

  • french

Programmes