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Neurosciences (part II) : maladies nerveuses
Course teacher(s)
Alban DE KERCHOVE D'EXAERDE (Coordinator) and Jerôme BonnefontECTS credits
5
Language(s) of instruction
french
Course content
Pathogenic mechanims in the nervous system: Programmed cell death and necrosis. Defects of DNA repair. Abnormalities of metabolic pathways. Excitotoxicity. Mitochondrial dysfunction. Disturbances of axoplasmic transport. Ubiquitin-proteasome system. Autophagy and intra- and extracellular accumulations of proteins.
Neurodegenerative diseases: Alzheimer's disease. Parkinson's disease. Huntigton's disease. Prions diseases. Amyotrophic lateral sclerosis. Neurogenetic diseases: Metabolic encephalopathies.
Hereditary Neurogenetic diseases: Hereditary diseases of the peripheral nervous system. Genetic epilepsies.
Normal and Pathological Mnesic Processes: Molecular and cellular mecanisms, types of memory, their neural supports and their alterations.
Neuropsychiatric Diseases: Drug addiction, Schizophrenia, Mood Disorders, Anxiety Disorders.
Objectives (and/or specific learning outcomes)
Acquisition of of basic knowledge related to pathologiocal cellular mechanisms of nervous diseases.
Prerequisites and Corequisites
Required and corequired courses
Teaching methods and learning activities
Theoretical courses: lectures.
Contribution to the teaching profile
Acquisition of scientific knowledges.
References, bibliography, and recommended reading
Reviews in scientific articles.
Other information
Contacts
Jean-Pierre Brion (coordonnateur): jpbrion@ulb.ac.be
Massimo Pandolfo:massimo.pandolfo@ulb.ac.be
Alban de Kerchove: Alban.de.Kerchove@ulb.ac.be
Evaluation
Method(s) of evaluation
- Other
Other
Written examination on the course content.
Mark calculation method (including weighting of intermediary marks)
If the three partial examination marks are equal or above 08/20: Pathogenic mechanisms and neurodegenerative diseases (J.P. Brion): 33 %; Pathogenic mechanisms and Neurogenetic diseases (M. Pandolfo): 33%. Mnesic Processes and Neuropsychaitric diseases (A. de Kerchove): 33%. If a a partai mark is inferior to 08/20, the maximal global examination mark is 07/20.
The examination marks inferior to 10/20 will not benefit from a partial report (J.P.Brion, M. Pandolfo, A. de Kerchove) to the next academic year.
Language(s) of evaluation
- french