Methods in Bioinformatics

This course provides an introduction to computational methods applied to biological questions. After an introduction to the computational biology domain, the notion of sequence aliment, motif discovery, protein structure will be detailed. A particular emphasis will be put on notion related to protein structure prediction and methods related to DNA and RNA Sequencing data analysis.

This course focusses on computational biology. The goal of this course is to provide students with the necessary skills i) to understand computational biology research, ii) to grasp the workings of some of the key algorithms that were developed to solve particular problems in molecular biology iii) to understand the role of different computational methods in solving these problems, iv) to know where certain molecular data can be found and how to combine this, v) to be able to develop a project that tries to solve some problem in this domain. In addition, this knowledge will allow you to understand the literature on bioinformatics and computational biology.

Cours co-requis

Oral presentations and scientific report.

References, bibliography, and recommended reading

Provided in the slides.

Contacts

Matthieu Defrance

Département d'Informatique

Université Libre de Bruxelles

Boulevard du Triomphe CP 212

1050 Brussels

Belgium

Tel: 02/650.58.68

Email: mathieu.defrance@ulb.be

Campus

Plaine

Method(s) of evaluation

• Other

Other

For the exam, students will present an article, discussing the context, methods. results and conclusions drawn by the authors.

The quality of the project and the quality of the presentation will determine the final points for this course.

Mark calculation method (including weighting of intermediary marks)

100% on the oral presentation and report.

Language(s) of evaluation

• english