Molecular and biomolecular engineering

Through the development of a Lateral Flow Assay (LFA) - a test similar to the pregnancy test, different aspects of the development of a molecular sensor are discussed: the synthesis, characterization and functionalization of nanomaterials, the use of biomolecules to provide selectivity, the validation of the test. 

Apply all acquired knowledge in chemistry to critically analyse the complex issues related to the production and use of a molecular sensor. In groups, and under the supervision of the teacher, students will have to find in the literature protocols to set up the test and apply them in the laboratory. The obtained results will have to report to the other students as a oral presentation and as a written scientific report. 

Students will have to work in groups on one of the three following topics:
- synthesis and characterization of the nanoparticles
- functionalization of the particles using a selected biomolecule
- functionalization of the cellulose membrane
- validation of the test.

Students will have to prepare a oral presentation for their colleagues presenting the requested theoretical concepts and the results that have been obtained experimentally.
The experimental results will also have to be reported as an scientific report to the teacher. 

EIB students will have to provide a personal work on a ethical, sociological or economical controversial issue. The topic can be related to the MA thesis. 

Contribution au profil d'enseignement

This teaching unit contributes to the following competences:

• In-depth knowledge and understanding of exact sciences with the specificity of their application to engineering
• The flexibility and adaptability to work in an international and/or intercultural context
• An integrated insight in chemical process and materials' technology
• Ability to reformulate complex engineering problems in order to solve them (simplifying assumptions, reducing complexity) 
• Ability to conceive, plan and execute a research project, based on an analysis of its objectives, existing knowledge and the relevant literature, with attention to innovation and valorization in industry and society 
• Report correctly on research or design results in the form of a technical report or in the form of a scientific paper 
• Present and defend results in a scientifically sound way, using contemporary communication tools, for a national as well as for an international professional or lay audience
• Collaborate in a (multidisciplinary) team
• Develop, plan, execute and manage engineering projects at the level of a starting professional 
• Think critically about and evaluate projects, systems and processes, particularly when based on incomplete, contradictory and/or redundant information
• Adopt a critical attitude towards one’s own results and those of others 
• Be conscious of the ethical, social, environmental and economic context of his/her work and strives for sustainable solutions to engineering problems including safety and quality assurance aspects 

Références, bibliographie et lectures recommandées

Chemical and Engineering News (American Chemical Society) - https://cen.acs.org

Support(s) de cours

• Université virtuelle

Contacts

Prof. Gilles Bruylants :e-mail: gilles.bruylants@ulb.be; bureau P2.2.110

Campus

Solbosch

Méthode(s) d'évaluation

• Travail personnel
• Présentation orale
• Travail de groupe

Travail personnel

Présentation orale

Travail de groupe

Presentation:

• Quality of the presentation
• Structure of the presentation
• Scientific content

Written report:

• Ability to synthesize
• Clarity of the reported results
• Analysis of the results and conclusions
• Wording, grammar, ease to read
• Bibliography

• Introduction/context
• State of the art/analysis of the existing solutions
• Personnel analysis/point of view
• Wording, grammar, ease to read
• Bibliography

Construction de la note (en ce compris, la pondération des notes partielles)

Personal work : 40%
Group presentation: 30%
Written report: 30%

Langue(s) d'évaluation

• anglais